Advanced Clinicals Professional Strength Retinol Anti Aging Serum (Discontinued)
Advanced Clinicals Professional Strength Retinol Anti Aging Serum was developed as a high-potency treatment to target fine lines, wrinkles, and uneven skin texture. Formulated with a base of soothing Aloe Barbadensis Leaf Juice rather than standard water, this serum aims to deliver the powerful anti-aging benefits of retinol while maintaining skin hydration. Key beneficial ingredients include Glycerin, a classic humectant, and Pyrus Malus (Apple) Fruit Extract, which provides antioxidant protection against environmental stressors. The inclusion of Hydrogenated Ethylhexyl Olivate suggests a smooth, emollient texture designed to buffer the potentially drying effects of retinol. Although this specific formula has been discontinued, it remains a notable example of a professional-strength serum that prioritizes a rich, moisturizing feel. However, the formulation's heavy reliance on certain esters and oils to create that creamy consistency is a significant point of consideration for users who are prone to congestion or active breakouts.
Our Analysis
Our analysis classifies this serum as having a HIGH comedogenic risk. The primary concern is Isopropyl Myristate, which ranks 5/5 on the comedogenic scale; this ingredient is known to penetrate deep into pores where it can harden and cause significant blockages. Furthermore, the formula contains Soybean Oil (3/5) and Olive Oil (2/5), which provide moisture but may exacerbate acne or fungal-related skin concerns. While Cetearyl Alcohol is typically manageable, its synergistic effect in a lipid-heavy formula like this increases the potential for 'creeping' comedogenicity. This serum may trigger breakouts in those with acne-prone skin despite its anti-aging claims.
Skin Type Recommendations
This serum is best suited for very dry or mature skin types that require intensive moisture and are not prone to acne. It is not recommended for oily, combination, or acne-prone skin due to the high concentration of Isopropyl Myristate and various oils that can lead to severe pore congestion.
Flagged Ingredients
Penetration enhancer that dives deep into pores and hardens, causing blockages.
Moderate comedogenicity; depends on the refinement level of the oil.
Fatty alcohol emollient with low-moderate comedogenicity on its own. However, when combined with Ceteareth-20, the synergistic effect can significantly increase pore-clogging potential (combined rating of 4).
High Oleic Acid content (similar to sebum); generally safe but can exacerbate fungal acne (Malassezia).
Pure Vitamin E is thick and sticky; safe in small amounts as an antioxidant, but potentially clogging in pure oil form.
Want Deeper Analysis?
Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.
