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Dr Macrene Dr Macrene High Performance Anti-Aging Cream - Product image showing packaging and label for comedogenic ingredient analysis
Dr MacreneMoisturizer

Dr Macrene High Performance Anti-Aging Cream

High Risk(15)
70 ingredients5 flagged

Dr Macrene High Performance Anti-Aging Cream is a luxury skincare formula designed to target the visible signs of aging with a potent blend of plant-derived actives and skin-replenishing emollients. This cream features a base of Dimethicone and Glycerin, providing a silky, smooth texture that immediately hydrates the skin and reinforces the moisture barrier. The inclusion of Trimethylolpropane Tricaprylate/Tricaprate ensures a sophisticated, elegant feel upon application, typical of high-end anti-aging treatments. While the product aims to deliver comprehensive rejuvenation, smoothing the appearance of fine lines and wrinkles, its rich formulation is complex. It seeks to provide a 'one-and-done' solution for mature skin, focusing on repair and antioxidant protection. However, users should look closely at the botanical and marine extracts included, as the richness of the texture is achieved through various fatty alcohols and thickening agents that may impact skin clarity for those prone to congestion.

Our Analysis

Our analysis classifies Dr Macrene High Performance Anti-Aging Cream as having a HIGH comedogenic risk level. The most significant concern is the presence of Algae Extract (5/5) and Plankton (4/5). These marine extracts are often high in iodides, which can irritate the pore lining and trigger inflammatory acne or micro-comedones. Furthermore, the inclusion of Cetyl Alcohol, Stearic Acid, and Tocopherol—while excellent for dry skin—adds to the potential for pore congestion. For users with clear, non-reactive skin, these ingredients provide nourishment, but for those with acne-prone tendencies, they present a high likelihood of causing breakouts.

Skin Type Recommendations

This cream is best for dry, very dry, and mature skin types that are not prone to acne. We strongly advise against using this product if you have oily, combination, or acne-prone skin, as the high concentration of algae and plankton extracts can lead to significant pore-clogging and irritation.

Flagged Ingredients

5
algae extract

Rich in iodides which irritate the pore lining, triggering inflammation and micro-comedones.

4
plankton

Marine extract often rich in iodides/minerals that can irritate pores.

2
cetyl alcohol

A fatty alcohol (emollient) that is generally safe, but can be problematic for very sensitive individuals.

2
stearic acid

Found in many butters; thickening agent with low-moderate risk.

2
tocopherol

Pure Vitamin E is thick and sticky; safe in small amounts as an antioxidant, but potentially clogging in pure oil form.

Want Deeper Analysis?

Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.

Full Ingredient List(70 ingredients)

WaterDimethiconeGlycerin (Plant-Derived)Cetyl Alcohol (Plant-Derived)Trimethylolpropane Tricaprylate/​TricaprateHelianthus Annuus (Sunflower) Seed Oil UnsaponifiablesStearic Acid (Plant-Derived)Sorbitan Stearate (Plant-Derived)ResveratrolPalmitoyl Tripeptide-1Palmitoyl Tetrapeptide-7Ferulic AcidPlankton ExtractBlue Algae ExtractMicrococcus LysateErgothioneineArabidopsis Thaliana ExtractBisabololCaffeineChrysanthemum Parthenium (Feverfew) Extract*Coffea Arabica (Coffee) Seed Extract*Helianthus Annuus (Sunflower) Seed OilHordeum Distichon (Barley) ExtractIlex Paraguariensis (Yerba Mate Tea) Leaf Extract*Phellodendron Amurense Bark ExtractSantalum Album (Sandalwood) ExtractTheobroma Cacao (Cocoa) Seed Butter*Tremella Fuciformis Polysaccharide (Mushroom Extract)GlucosamineMagnesium Ascorbyl PhosphateTetrahexyldecyl AscorbateTocopherolAlanineArginineAspartic AcidGlycineHistidineIsoleucinePcaPhenylalanineProlineSerineSodium PcaThreonineValineSodium HyaluronateSodium LactateHydrogenated (Soy) LecithinSqualaneLecithinHydrolyzed Soy ProteinXanthan Gum (Plant-Derived)Sodium Methyl Stearoyl TaurateHydroxypropyl Methylcellulose Stearoxy Ether (Plant-Derived)Sodium HydroxideButylene GlycolLaurdimonium Hydroxypropylmethylcellulose (Plant-Derived)AlcoholHydroxyethylcellulose (Plant-Derived)Caprylyl GlycolDisodium EdtaPhenoxyethanolHexylene GlycolEthylhexylglycerin (Plant-Derived)Polysorbate-20 (Plant-Derived)CarbomerTrimethylolpropane Tricaprylate/TricaprateRead all the geeky details about Glycerin here >>Read all the geeky details about Tocopherol here >>[more]

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Our analysis is powered by AI and backed by extensive research on comedogenic ingredients — but it's not medical advice. For skin concerns, please consult a dermatologist.