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La Roche-Posay La Roche-Posay Toleriane Ultra Overnight Sensitive Moisturiser - Product image showing packaging and label for comedogenic ingredient analysis
La Roche-PosayMoisturizer

La Roche-Posay Toleriane Ultra Overnight Sensitive Moisturiser

Low Risk(2)
32 ingredients1 flagged

La Roche-Posay Toleriane Ultra Overnight Sensitive Moisturiser is a specialized nighttime treatment designed to intensely hydrate and soothe reactive skin while you sleep. Part of the renowned Toleriane range, this moisturizer is formulated with a minimalist approach to minimize the risk of irritation and redness. The presence of high-quality humectants like Glycerin and Propanediol ensures deep moisture retention, while Squalane—a skin-identical lipid—provides a nourishing, non-greasy finish that mimics the skin's natural oils. This product is specifically crafted for ultra-sensitive or allergy-prone skin, aiming to restore the skin barrier and reduce sensitivity over time. The texture is lightweight yet comforting, making it an ideal choice for those who need deep moisture without the heavy, suffocating feel of traditional night creams. It effectively targets dryness and discomfort, leaving the complexion feeling refreshed and calm by morning. Without added fragrances or alcohols, it focuses on pure recovery.

Our Analysis

Our analysis classifies the La Roche-Posay Toleriane Ultra Overnight Sensitive Moisturiser as having a LOW comedogenic risk. The formula is primarily composed of skin-friendly ingredients like Squalane and Glycerin, which are excellent for hydration without clogging pores. The only flagged ingredient is tocopherol (Vitamin E), which carries a 2/5 rating. While pure Vitamin E can be thick and sticky, in this professionally balanced formulation, it serves as a vital antioxidant to protect the skin barrier. For most users with acne-prone skin, this level of risk is negligible, making it a generally safe and effective choice for nightly hydration.

Skin Type Recommendations

This moisturizer is ideal for sensitive, dry, and combination skin types. Its minimalist, low-risk formula makes it a strong candidate for those with acne-prone skin who struggle with barrier damage or irritation. While suitable for oily skin, the squalane-based hydration provides a rich finish that dry skin will particularly love.

Flagged Ingredients

2
tocopherol

Pure Vitamin E is thick and sticky; safe in small amounts as an antioxidant, but potentially clogging in pure oil form.

MACR Analysis

5-Axis AI-Powered Risk Assessment

Overall Risk Score

Lower is better

13/100
Low Risk

Score by Skin Type

Lower is better

Dry9Can Try
Oily14Can Try
Sensitive7Can Try
Acne-Prone14Can Try

Same product, different risks based on your skin type

Detected: unknown

Fallback analysis found 1 potentially comedogenic ingredients with an overall risk score of 13/100.

Risk Breakdown

(PR) Plugging Risk1.0/5
(BR) Barrier Risk0.0/5
(FR) Fungal Risk0.0/5
(OR) Oxidation Risk0.0/5
(UR) User-Reported2.0/5

Skin Type Considerations

Oily/Acne-Prone:May cause breakouts for acne-prone skin
Fungal Acne-Prone:May be suitable for fungal acne
Dry/Sensitive:See full analysis for details
AI Confidence: 50%Used fallback analysis

This analysis uses the Multi-Axis Comedogenic Risk (MACR) system. Results are AI-estimated and cannot account for actual ingredient concentrations. Individual reactions may vary. Consult a dermatologist for personalized advice.

Full Ingredient List(32 ingredients)

Aqua /​ WaterGlycerinSqualanePropanediolButylene GlycolButyrospermum Parkii Butter /​ Shea ButterPentylene GlycolNiacinamideDimethiconeAmmonium Polyacryldimethyltauramide /​ Ammonium Polyacryloyldimethyl TauratePolymethylsilsesquioxanePolysorbate 20AllantoinGlyceryl Acrylate/​Acrylic Acid CopolymerDimethiconolAluminum Starch OctenylsuccinateCarnosineDisodium EdtaCitric AcidAcetyl Dipeptide-1 Cetyl EsterXanthan GumT-Butyl AlcoholToluene Sulfonic AcidTocopherolAqua / WaterButyrospermum Parkii Butter / Shea ButterAmmonium Polyacryldimethyltauramide / Ammonium Polyacryloyldimethyl TaurateGlyceryl Acrylate/Acrylic Acid CopolymerRead all the geeky details about Glycerin here >>Read all the geeky details about Niacinamide here >>Read all the geeky details about Tocopherol here >>[more]

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Our analysis is powered by AI and backed by extensive research on comedogenic ingredients — but it's not medical advice. For skin concerns, please consult a dermatologist.