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The Chemistry Brand The Chemistry Brand Hand Chemistry - Product image showing packaging and label for comedogenic ingredient analysis
The Chemistry Brand

The Chemistry Brand Hand Chemistry

Moderate Risk(8)
36 ingredients4 flagged

The Chemistry Brand Hand Chemistry is a concentrated multi-functional hand cream designed to target multiple signs of hand aging simultaneously. Formulated by the innovative team at DECIEM, this product goes beyond simple hydration to improve the look of firmness, elasticity, density, and skin evenness. The formula is anchored by Aqua and Caprylic/Capric Triglyceride, providing a smooth, emollient texture that absorbs effectively without leaving an excessively greasy residue. With Propanediol acting as a humectant, it helps pull moisture into the skin, while fatty alcohols like Cetearyl Alcohol and Cetyl Alcohol provide a protective barrier to prevent trans-epidermal water loss. The inclusion of Tocopherol (Vitamin E) adds a layer of antioxidant protection against environmental stressors. While primarily designed for the hands, its rich and nourishing texture is ideal for those dealing with chronic dryness or loss of skin volume. However, because our hands frequently touch our faces throughout the day, the ingredient profile is worth a closer look for those with highly reactive or acne-prone skin.

Our Analysis

Our analysis of The Chemistry Brand Hand Chemistry reveals a Moderate comedogenic risk level. The formula contains several ingredients that can be problematic for acne-prone individuals, specifically Caprylic/Capric Triglyceride and fatty alcohols like Cetearyl and Cetyl Alcohol. While these ingredients are excellent for repairing the skin barrier on the hands, they carry individual comedogenic ratings of 2/5. We specifically flag Cetearyl Alcohol as it can become more pore-clogging when combined with specific surfactants. Additionally, Tocopherol (Vitamin E) is present; while a great antioxidant, it can be heavy for some skin types. This product is best kept to the hands.

Skin Type Recommendations

This hand cream is best suited for dry, aging, or mature skin that requires intense moisture and barrier repair. It is not recommended for facial application on oily or acne-prone skin due to the moderate comedogenic risk of its emollients. Use with caution if you have highly sensitive, breakout-prone skin.

Flagged Ingredients

2
capric/caprylic triglyceride

Fractionated coconut oil; removed most clogging long-chain acids but can still affect some.

2
cetearyl alcohol

Fatty alcohol emollient with low-moderate comedogenicity on its own. However, when combined with Ceteareth-20, the synergistic effect can significantly increase pore-clogging potential (combined rating of 4).

2
cetyl alcohol

A fatty alcohol (emollient) that is generally safe, but can be problematic for very sensitive individuals.

2
tocopherol

Pure Vitamin E is thick and sticky; safe in small amounts as an antioxidant, but potentially clogging in pure oil form.

Want Deeper Analysis?

Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.

Full Ingredient List(36 ingredients)

Aqua (Water)Caprylic/​Capric TriglyceridePropanediolCetearyl GlucosideCetearyl AlcoholGlycerinCetyl AlcoholPlukenetia Volubilis Seed OilCopper Lysinate/​ProlinatePlantago Lanceolata Leaf ExtractMethylglucoside PhosphateProlineAlanineSerinePseudoalteromonas Ferment ExtractTremella Fuciformis Sporocarp ExtractTocopherolBetaineCelluloseXanthan GumSodium PolyacrylateSodium PhosphateSodium HydroxidePotassium SorbateCaprylyl GlycolEthylhexylglycerinPhenoxyethanolChlorphenesinParfum (Fragrance)LimoneneLinaloolCaprylic/Capric TriglycerideCopper Lysinate/ProlinateRead all the geeky details about Glycerin here >>Read all the geeky details about Tocopherol here >>[more]

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Our analysis is powered by AI and backed by extensive research on comedogenic ingredients — but it's not medical advice. For skin concerns, please consult a dermatologist.