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Bioderma Bioderma Matricium - Product image showing packaging and label for comedogenic ingredient analysis
BiodermaExfoliant

Bioderma Matricium

Moderate Risk(5)
67 ingredients1 flagged

Bioderma Matricium is a unique, sterile treatment designed to promote tissue regeneration and skin recovery. Classified as a medical device rather than a standard cosmetic, it aims to create the ideal micro-environment for the skin to heal itself from within. The formula is packed with skin-identical nutrients, including Sodium Hyaluronate for deep hydration and Alanyl Glutamine to support cellular repair. Because it is formulated as a series of sterile single-use ampoules, the texture is incredibly lightweight and watery, absorbing instantly into the skin without any greasy residue. It is frequently recommended by dermatologists for skin recovering from aesthetic procedures, superficial burns, or severe irritation. However, for those tracking ingredient safety for acne-prone skin, the inclusion of certain mineral salts requires a closer look. While it offers impressive regenerative properties, its complex blend of amino acids, vitamins, and minerals must be weighed against its comedogenic potential. It provides an essential boost for damaged barriers, but users should be mindful of how specific components interact with their pore health.

Our Analysis

Our analysis of Bioderma Matricium reveals a Moderate comedogenic risk level. While it contains highly beneficial skin-repairing ingredients, we flagged Potassium Chloride, which carries a high comedogenic rating of 5/5. This mineral salt is known to cause significant irritation and can lead to follicular hyperkeratosis—a process where the skin's outer layer thickens and contributes to blocked pores. For those with highly reactive or acne-prone skin, this specific ingredient could potentially trigger breakouts despite the product’s restorative intentions. It is important to monitor your skin's reaction carefully if you are prone to congestion.

Skin Type Recommendations

This product is best suited for dry, dehydrated, or compromised skin needing intensive repair after dermatological procedures. However, it is not recommended for oily or acne-prone skin types. The presence of Potassium Chloride makes it high-risk for those prone to clogged pores, potentially exacerbating breakouts while attempting to heal the surface.

Flagged Ingredients

5
potassium chloride

Mineral salt known to cause significant irritation and follicular hyperkeratosis.

Want Deeper Analysis?

Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.

Full Ingredient List(67 ingredients)

Aqua/​Water/​EauSodium ChlorideGlucoseSodium HyaluronateAlanyl GlutamineDisodium PhosphateArginine HclSodium AcetateLactis Proteinum/​Whey Protein/​Proteine Du Petit LaitSerineLeucineMagnesium ChloridePotassium ChlorideMannitolFructooligosaccharidesRhamnoseXylitolValineSodium PyruvateLysine HclHistidine HclProlineCysteine HclHydroxyprolineGlutamic AcidAsparagineThreonineInositolAdenineAlanineAspartic AcidGlycineMethionineTyrosinePhenylalanineTryptophanLactic AcidIsoleucineSodium SulfateFolic AcidFerrous SulfateCalcium PantothenateThiamine HclPyridoxine HclNiacinamideAscorbic AcidThymidineCyanocobalaminThioctic AcidRiboflavinSodium MetasilicateZinc SulfateAdenosineGuanineDeoxyriboseRiboseBiotinAmmonium MolybdateAmmonium VanadateCopper SulfateManganese ChlorideAqua/Water/EauLactis Proteinum/Whey Protein/Proteine Du Petit LaitRead all the geeky details about Lactic Acid here >>Read all the geeky details about Niacinamide here >>Read all the geeky details about Ascorbic Acid here >>[more]

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Our analysis is powered by AI and backed by extensive research on comedogenic ingredients — but it's not medical advice. For skin concerns, please consult a dermatologist.