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NIOD NIOD Copper Amino Isolate Serum 5% - Product image showing packaging and label for comedogenic ingredient analysis
NIODSerum

NIOD Copper Amino Isolate Serum 5%

Low Risk(0)
34 ingredients

NIOD Copper Amino Isolate Serum 5% (CAIS5) is a highly concentrated pro-repair, pro-collagen treatment designed to maintain skin health at a fundamental level. Unlike traditional anti-aging serums that target specific signs of aging, this advanced formula focuses on skin longevity and repair using a potent 5% concentration of pure Copper Tripeptide-1. This peptide is naturally found in human plasma and is celebrated for its ability to support wound healing, collagen synthesis, and anti-inflammatory processes. Supported by a complex of Methylglucoside Phosphate and Copper Lysinate/Prolinate, this serum helps to improve skin elasticity, clarity, and overall texture over time. The formula features a lightweight, water-like consistency that absorbs instantly into the skin without leaving any heavy or greasy residue. This makes it an excellent choice for layering in a multi-step routine. Glycerin provides a foundational layer of humectant hydration, ensuring the skin remains supple while the active copper peptides work to remodel the skin’s appearance. For those seeking a high-performance serum that addresses texture and fine lines without the risk of clogging pores, NIOD CAIS 5% offers a sophisticated, science-forward solution.

Our Analysis

Our analysis of NIOD Copper Amino Isolate Serum 5% confirms a Low Comedogenic Risk. The formulation is remarkably clean, intentionally excluding common pore-clogging waxes, heavy oils, and synthetic thickeners that often trigger breakouts in acne-prone individuals. The primary ingredients, including Glycerin and various Copper complexes, are non-comedogenic and water-soluble. With no flagged ingredients found in the list, this serum is considered safe for those who struggle with congestion or active acne. It provides intensive repair benefits and anti-aging support without the typical risk of aggravating acne or causing new comedones.

Skin Type Recommendations

This serum is ideal for all skin types, particularly oily, combination, and acne-prone skin, thanks to its oil-free, water-based texture. Its anti-inflammatory properties are also excellent for sensitive skin. While dry skin types will benefit from the glycerin and copper peptides, they should follow up with a non-comedogenic moisturizer.

Flagged Ingredients

No High-Risk Ingredients

This product does not contain known high-risk comedogenic ingredients.

Want Deeper Analysis?

Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.

Full Ingredient List(34 ingredients)

Glycerin*Copper Tripeptide-1*Aqua (Water)*Methylglucoside Phosphate*Copper Lysinate/​Prolinate*Ppg-26-Buteth-26*Peg-40 Hydrogenated Castor Oil*Chlorphenesin*Phenoxyethanol*Aqua (Water)**Sodium Hyaluronate Crosspolymer**Glycerin**Dimethyl Isosorbide**Ethoxydiglycol**Decapeptide-22**Ogliopeptide-78**Palmitoyl Decapeptide-21**Zinc Palmitoyl Nonapeptide-14**Myristoyl Nonapeptide-3**Hydrolyzed Wheat Protein**Pentylene Glycol**Ppg-26-Buteth-26**Peg-40 Hydrogenated Castor Oil**Xanthan Gum**Caprylyl Glycol**Glyceryl Caprylate**Phenylpropanol**Ethylhexylglycerin**Chlorphenesin**Phenoxyethanol**Copper Lysinate/Prolinate*Read all the geeky details about Glycerin here >>Read all the geeky details about Copper Tripeptide-1 here >>[more]

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Our analysis is powered by AI and backed by extensive research on comedogenic ingredients — but it's not medical advice. For skin concerns, please consult a dermatologist.