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Paula's Choice Paula's Choice Resist Super Antioxidant Serum - Product image showing packaging and label for comedogenic ingredient analysis
Paula's ChoiceSerum

Paula's Choice Resist Super Antioxidant Serum

Moderate Risk(6)
28 ingredients2 flagged

Paula’s Choice Resist Super Antioxidant Serum is a high-performance formula designed to defend the skin against environmental damage while targeting the visible signs of aging. This serum features a sophisticated blend of stable Vitamin C (Tetrahexyldecyl Ascorbate) to brighten the complexion and Palmitoyl Tripeptide-5 to support skin firmness. The inclusion of Ceramide NP helps to replenish the skin’s natural moisture barrier, ensuring a healthy and hydrated appearance. With a base of Cyclopentasiloxane and Dimethicone, the texture is silky and smooth, providing a lightweight, velvet-like finish that layers well under moisturizer or makeup. It is specifically formulated to revitalize dull skin and neutralize free radicals. While it offers an impressive array of skin-restoring ingredients, those with specific sensitivities or acne-prone skin should look closely at the ingredient profile. This serum provides a nourishing feel that dry and mature skin types will particularly appreciate, though the formulation contains specific oils that may impact those with highly reactive or congestion-prone pores.

Our Analysis

Our analysis of the Paula’s Choice Resist Super Antioxidant Serum indicates a Moderate comedogenic risk level. While the formula is packed with beneficial antioxidants, it contains palm oil, which carries a high comedogenic rating of 4/5. Palm oil is rich in palmitic acid, which can create a heavy, occlusive film that may lead to breakouts in susceptible individuals. Additionally, the serum contains tocopherol (Vitamin E), which, while excellent for skin health, can be thick and potentially clogging in certain concentrations. If you struggle with active acne or frequent congestion, these specific ingredients may be problematic.

Skin Type Recommendations

This serum is ideal for dry, normal, and mature skin types seeking anti-aging benefits and barrier repair. However, due to the inclusion of palm oil and tocopherol, it is not recommended for oily or severely acne-prone skin. Combination skin types should use it cautiously and monitor for any signs of new congestion.

Flagged Ingredients

4
palm oil

High saturated fat (Palmitic Acid) content creates a heavy, clogging film.

2
tocopherol

Pure Vitamin E is thick and sticky; safe in small amounts as an antioxidant, but potentially clogging in pure oil form.

Want Deeper Analysis?

Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.

Full Ingredient List(28 ingredients)

CyclopentasiloxaneDimethiconeTetrahexyldecyl AscorbatePalmitoyl Tripeptide-5Ceramide NPTocotrienolsTocopherolUbiquinoneThioctic AcidTocopheryl AcetateMagnesium Ascorbyl PhosphateFerulic AcidBeta-GlucanSuperoxide DismutaseEpigallocatechin GallateErgothioneineGlutathioneXanthophyllsGlycine Soja Seed ExtractGlycerinArctostaphylos Uva-Ursi Leaf ExtractLupinus Albus Seed OilCurcuma Longa Root ExtractElaeis Guineensis OilPhenoxyethanolRead all the geeky details about Tocopherol here >>Read all the geeky details about Glycerin here >>[more]

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Our analysis is powered by AI and backed by extensive research on comedogenic ingredients — but it's not medical advice. For skin concerns, please consult a dermatologist.